教职员工

陈国颂 教授

上海市杨浦区淞沪路2005号 复旦大学江湾校区化学-高分子楼B4080(200438)
电话:021-31244275
传真:021-31244275
邮箱:guosong@fudan.edu.cn
主页:http://www.polymer.fudan.edu.cn/polymer/research/CGSJM/EN/Default.aspx

教育和工作经历

1997-2001 南开大学 化学学士
2001-2006 南开大学 物理化学博士
2006-2009 美国爱荷华州立大学化学系 有机化学博士后
2009-2011 复旦大学 讲 师
2011-2014 复旦大学 副教授
2014-至今 复旦大学 教 授、博士生导师

研究兴趣

  • 利用糖-蛋白质相互作用构筑蛋白质规则组装体和晶体
  • 基于糖的大分子组装体的免疫学功能
  • 糖化学反应驱动的大分子自组装

近年代表性论文

  1. Wenjing Qi, Yufei Zhang, Jue Wang, Guoqing Tao, Libin Wu, Zdravko Kochovski, Hongjian Gao, Guosong Chen*, Ming Jiang, “Deprotection-induced morphology transition and immuno-activation of glyco-vesicles: a strategy of smart delivery polymersomes” J. Am. Chem. Soc., 2018, 140, 8851-8857.
  2. Yufei Zhang, Libin Wu, Zhen Li, Weiyi Zhang, Feifei Luo, Yiwei Chu, Guosong Chen*, “Glycocalyx-Mimicking Nanoparticles Improve Anti-PD-L1 Cancer Immunotherapy through Reversion of Tumor-Associated Macrophages” Biomacromolecules 2018, 19, 2098-2108. (Invited in Biomacromolecules Asian Special Issue)
  3. Libin Wu, Yufei Zhang, Zhen Li, Guang Yang, Zdravko Kochovski, Guosong Chen*, Ming Jiang, “"Sweet" Architecture-Dependent Uptake of Glycocalyx-Mimicking Nanoparticles Based on Biodegradable Aliphatic Polyesters by Macrophages” J. Am. Chem. Soc.2017, 139, 14684-14692.
  4. Wei Zheng, Guang Yang, Nannan Shao, Li-Jun Chen, Bo Ou, Shu-Ting Jiang, Guosong Chen*, Haibo Yang*, “CO2 Stimuli-Responsive, Injectable Block Copolymer Hydrogels Cross-linked by Discrete Organoplatinum(II) Metallacycles via Stepwise Post-Assembly Polymerization”, J. Am. Chem. Soc., 2017, 139, 13811-13820.
  5. Guang Yang, Hong-ming Ding, Zdravko Kochovski, Rongting Hu, Yan Lu, Yu-qiang Ma*, Guosong Chen*, Ming Jiang “Highly ordered self-assembly of native proteins into 1D, 2D and 3D structures modulated by a tether length of inducing ligands”, Angew. Chem. Int. Ed2017, 56, 10691-10695.
  6. Yu Zhao, Yufei Zhang, Changchun Wang, Guosong Chen*, Ming Jiang, “Role of Protecting Groups in Synthesis and Self-Assembly of Glycopolymers”, Biomacromolecules 2017, 18, 568-575.
  7. Zhen Li, Liang Sun, Yufei Zhang, Andrew P Dove, Rachel K. O'Reilly*, Guosong Chen*, “Shape Effect of Glyco-Nanoparticles on Macrophage Uptake and Immune Response”, ACS Macro Lett.2016, 5, 1059-0164.
  8. Yijiang Liu, Yufei Zhang, Zheyu Wang, Jue Wang, Kongchang Wei, Guosong Chen*, Ming Jiang, “Building Nanowires from Micelles: Hierarchical Self-assembly of Alternating Amphiphilic Glycopolypeptide Brushes with Pendants of High-Mannose Glycodendron and Oligophenylalanine”, J. Am Chem. Soc. 2016, 138, 12387-12394. 
  9. Guang Yang, Libin Wu, Guosong Chen*, Ming Jiang, “Precise Protein Assembly to Array Structures”, Chem. Commun.2016, 52, 10595-10605.
  10. Zhongwei Ji, Junfang Li, Guosong Chen*, Ming Jiang, “Fate of Host-Stabilized Charge Transfer Complexation Based on Cucurbit[8]uril: Inducing Cyclization of PNIPAM and Dissociation in Self-Assembly of the Cyclic Polymer”, ACS Macro Lett2016, 5, 588-592.
  11. Wei Zheng, Li-Jun Chen, Guang Yang, Bin Sun, Xu Wang, Bo Jiang, Guang-Qiang Yin, Li Zhang, Xiaopeng Li, Minghua Liu, Guosong Chen*, Haibo Yang*, “Construction of Smart Supramolecular Polymeric Hydrogels Cross-linked by Discrete Organoplatinum(II) Metallacycles via Post-Assembly Polymerization”, J. Am. Chem. Soc., 2016, 138, 4927-4937.
  12. Guang Yang, Xiang Zhang, Zdravko Kochovski, Yufei Zhang, Bin Dai, Fuji Sakai, Lin Jiang, Yan Lu, Matthias Ballauff, Xueming Li, Cong Liu*, Guosong Chen*, Ming Jiang, “Precise and Reversible Protein-Microtubule-Like Structure with Helicity Driven by Dual Supramolecular Interactions”, J. Am. Chem. Soc., 2016, 138, 1932-1937.

主要荣誉与奖励

  • 2018 ACS PMSE Young Investigator Award
  • 2018 Nano Research Young Innovator Awards (NR45) 
  • 中组部“万人计划”青年拔尖人才(2014)
  • 国家自然科学基金委优秀青年基金(2013)
  • 上海市教委曙光计划(2013)
  • 上海市科委青年科技启明星(A类)(2013)
  • 第6届冯新德高分子奖(与江明教授共享)

学术兼职

  • Associate Editor ACS Macro Letters 
  • Fellow of Royal Society of Chemistry (FRSC)
  • 中国化学会高分子学科委员会委员
  • Editorial Advisory Board Polymer Chemistry, Bioconjugate Chemistry, Polymer International, J. Macro. Sci. Part A.
  • 《中国科学化学》青年编委

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